IMR Press / EJGO / Volume 40 / Issue 3 / DOI: 10.12892/ejgo4537.2019
Open Access Case Report
Postpartum choriocarcinoma: a rare case report and review of literature
Na Guo1,2R. Yin1,2Q. Li1,2L. Song1,2D. Wang1,2,*
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1 The Department of Obstetrics and Gynecology, West China Second University Hospital of Sichuan University, Chengdu, Sichuan, China
2 Key laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Sichuan, China
Eur. J. Gynaecol. Oncol. 2019, 40(3), 480–483; https://doi.org/10.12892/ejgo4537.2019
Published: 10 June 2019
Abstract

Background: Postpartum choriocarcinoma is a rare complication of pregnancy; early diagnosis is important because this rare condition is potentially curable with appropriate chemotherapy. Case Report: Twenty-nine women with postpartum choriocarcinoma were treated at West China Second University Hospital. The most common symptom among the 29 patients with postpartum choriocarcinoma was irregular vaginal bleeding (27/29), one patient had amenorrhea symptoms (1/29), and one patient with ultrasound showed uterine lesion with no symptom (1/29). Diagnosis was made by the level of serum β-hCG, pelvic ultrasound, and radiological investigation. Treatment with multiagent chemotherapy was successful in all cases. Conclusions: The most common symptom of patients with postpartum choriocarcinoma was genital bleeding, and the overall prognosis may be improved by early diagnosis and an appropriate chemotherapy regimen.

Keywords
Postpartum choriocarcinoma
Early diagnosis
Clinical manifestation
Gestational trophoblast tumor
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