IMR Press / EJGO / Volume 4 / Issue 2 / pii/1983026

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Original Research

α-L-fucosidase activity in endometrial, cervical and ovarian cancer

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1 Department of Obstetrics and Gynecology, University of Ferrara (Italy)
2 Institute of General Physiology, University of Ferrara (Italy)
Eur. J. Gynaecol. Oncol. 1983, 4(2), 135–138;
Published: 10 June 1983

α-L-fucosidase activity assayed on endometrial, cervical and ovarian tissue in benign and malignant conditions has been found to be increased m cancer tissue. Knowing that α-L-fucose plays a fundamental role in the process of inhibition of macrophages migration, increased activity of fucosidase in tumors can be interpreted as a possible mechanism by which cancer cells directly subvert the process of macrophages activation thus facilitating xenoplastic growth.

Cancer immunology
Enzyme activity
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