IMR Press / EJGO / Volume 4 / Issue 2 / pii/1983016

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research

The significance of measurement of several oncofetal antigens in diagnosis and management of epithelial ovarian tumors

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1 Institute of Obstetrics and Gynecology, University of Florence, Italy
2 Institute of Nuclear Medicine, University of Florence, Italy
3 Clinic of Nuclear Medicine, USL 10/D Florence, Italy
Eur. J. Gynaecol. Oncol. 1983, 4(2), 88–93;
Published: 10 June 1983

Association of serum alphafetoprotein (αFP), human chorionic gonadotropin β-subunit (β-HCG), carcinoembryonic antigen (CEA) and ferritin (FER) was studied in a group of 72 patients with epithelial ovarian cancer 15 days after surgery and at various times during 2 years. Only CEA and ferritin are able to reflect tumor burden in detecting evolutive disease; αFP and β-HCG have a diagnostic significance in few cases, probably related to a particular, not evident, histological component of the tumor. Nevertheless the data indicate that the use of marker association can improve our capacity to detect, overall in the residual and evolutive disease, the real clinical burden of the patients.

Ovarian neoplasms
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