IMR Press / EJGO / Volume 39 / Issue 5 / DOI: 10.12892/ejgo3980.2018

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Original Research
Prevalence of HPV and genotype distribution in “catch-up” HPV vaccinated women
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1 Department of Obstetrics and Gynaecology, University of Medicine and Pharmacy "Grigore T.Popa", Iasi, Romania
2 Department of Epidemiology, University of Medicine and Pharmacy "Grigore T.Popa", Iasi, Romania
3 Department of Biochemistry, University of Medicine and Pharmacy "Grigore T.Popa", Iasi, Romania
4 Department of Pathology, University of Medicine and Pharmacy "Grigore T.Popa", Iasi, Romania
Eur. J. Gynaecol. Oncol. 2018, 39(5), 760–763; https://doi.org/10.12892/ejgo3980.2018
Published: 10 October 2018
Abstract

Purpose of investigation: The aim of the present study was to evaluate the prevalence of HPV and genotype distribution among HPVvaccinated women. Material and Methods: The authors recruited 147 women, which were vaccinated through “catch-up vaccination”, five years before this study. The authors analyzed the presence of HPV, genotype distribution, and risk factors for HPV infections. Results: The relative prevalence of HPV/DNA was as follows: out of the total 147 tested samples, 19 samples (12.92%) were positive for HPV/DNA, 11 of which (7.48%) were single type HPV infections, and eight (5.44%) tested positive for multiple HPV genotypes. The most frequent genotypes were: 16, followed by 35, 56, and 31. Low risk genotypes 6 and 11 were present together in one case. Conclusion: The results showed a decrease in HPV prevalence 16/18 in vaccinated women through a catch-up vaccination, suggesting good effects of the previous HPV immunization program.
Keywords
HPV infection
HPV vaccine
“Catch-up” vaccination
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