IMR Press / EJGO / Volume 39 / Issue 5 / DOI: 10.12892/ejgo3849.2018

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Case Report
Synchronous cervical and endometrial carcinomas treated by external beam radiotherapy and californium-252 neutron brachytherapy: a case report
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1 Cancer Center, Daping Hospital and Institute of Surgery Research, Third Military Medical University, Chongqing, China
Eur. J. Gynaecol. Oncol. 2018, 39(5), 817–820;
Published: 10 October 2018

Background: Synchronous primary malignant neoplasms of the uterus are uncommon. Patients with synchronous cervical and endometrial cancers are even rarer. Materials and Methods: Presented is a case of histologically distinct cervical squamous cell carcinoma and endometrial adenocarcinoma occurring simultaneously in a 50-year-old woman with a 1-month history of postmenopausal uterine bleeding. Both simultaneous genital tract neoplasms were treated by a combination of external beam radiotherapy EBRT and californium-252 neutron brachytherapy. Results: As of March 2016, the patient has survived for nearly 4 years (complete remission). Late radiation proctitis, known to cause serious morbidity (G2), was observed half a year after the end of radiotherapy, however the signs of proctitis subsided by the use of dexamethasone. Conclusion: pelvic EBRT combined with Cf-252 neutron brachytherapy for the treatment of synchronous primary malignant neoplasms of the uterus is effective with tolerance complications.
cervical cancer
endometrial cancer
synchronous primary malignancies
Cf-252 neutron brachytherapy
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