IMR Press / EJGO / Volume 39 / Issue 2 / DOI: 10.12892/ejgo3872.2018

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Original Research
Case analysis of fertility-preserving treatment in female patients with malignant ovarian cancer
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1 Department of Gynecology, Hainan General Hospital, Haikou, China
2 Department of Radiology, Hainan General Hospital, Haikou, China
Eur. J. Gynaecol. Oncol. 2018, 39(2), 216–220; https://doi.org/10.12892/ejgo3872.2018
Published: 10 April 2018
Abstract

The aim of this study was to evaluate the impacts of fertility-preserving surgery and chemotherapy on the fertility and ovarian functions in malignant ovarian cancer. The clinical data of 52 female patients with malignant ovarian cancer and performed fertility-preserving treatment (FPT) in the present hospital between June 2004 and December 2014 were retrospectively analyzed. The 52 cases included 25 cases of germ cell carcinoma (GCC) (48.07%), 12 cases of epithelial ovarian carcinoma (EOC) (23.07%), and 15 cases of borderline carcinoma (28.84%), among which one case recurred (1.92%) and one died (1.92%). Forty-five cases had normal menstruation after the treatment (86.53%), and 16 cases out of the 27 cases with fertility requirement successfully achieved pregnancy (59.26%). FPT in female patients with malignant ovarian cancer was effective and feasible; although chemotherapy might affect ovarian function, it could also be reversed. Ovarian tumor resection or adnexectomy may be the best way for fertility preserving treatments; however, further investigation is warranted.
Keywords
Ovarian cancer
Fertility-preserving treatment
Surgery
Chemotherapy
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