IMR Press / EJGO / Volume 39 / Issue 2 / DOI: 10.12892/ejgo3855.2018

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Case Report
Uterine leiomyosarcoma with skeletal muscle metastasis
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1 Department of Obstetrics and Gynecology, Mutah University, Karak, Jordan
2 Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital at Linkou and Chang Gung University College of Medicine, Kweishan, Taoyuan, Taiwan
3 Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital at Linkou and Chang Gung University College of Medicine, Kweishan, Taoyuan, Taiwan
4 Department of Pathology, Chang Gung Memorial Hospital at Linkou and Chang Gung University College of Medicine, Kweishan, Taoyuan, Taiwan
Eur. J. Gynaecol. Oncol. 2018, 39(2), 307–309; https://doi.org/10.12892/ejgo3855.2018
Published: 10 April 2018
Abstract

Background: Leiomyosarcoma of the uterus is a rare tumor; hence there is lack of evidence on the tumor behavior in terms of prognostic factor for recurrence and its metastatic pattern. Practitioners usually find difficulty in choosing the best management options in treating rare diseases. Case Report: A case of uterine leiomyosarcoma underwent staging laparoscopy and adjuvant chemotherapy. First recurrence was discovered as a single lung nodule after two years follow up, so the patient underwent a metastatectomy. Second recurrence was isolated right biceps muscle metastasis which was removed and followed by chemo-radiotherapy. Patient died one year following the second recurrence. Conclusion: There are no specific pathological findings or independent factors which can predict the metastatic pattern or the site of recurrence. Surgical resection appears to be the best option in management of leiomysarcoma metastasis if feasible. Evidence supports the roll of chemotherapy in non-operable recurrence.
Keywords
Leiomyosarcoma
Metastasis
Recurrence site
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