IMR Press / EJGO / Volume 39 / Issue 2 / DOI: 10.12892/ejgo3747.2018

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Case Report
Metastatic recurrence after a pT1a grade 1 endometrioid endometrial adenocarcinoma
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1 Medical Oncology Unit, Institut de Cancérologie du Gard, Nîmes, France
Eur. J. Gynaecol. Oncol. 2018, 39(2), 314–315; https://doi.org/10.12892/ejgo3747.2018
Published: 10 April 2018
Abstract

Developement metastasis in grade 1 endometrioid cancer is unusual. The author reports the case of a 71-year-old patient who presented with liver metastasis, peritoneal mets, and pulmonary lymphangitis. Two years before, she had been diagnosed with a pT1a Stage 1 endometrioid adenocarcinoma of the uterus. She underwent surgery: total hysterectomy and bilateral salpingo-oophorectomy. Histologically it was a Stage 1, grade 1, pT1a endometrioid-type endometrial cancer. There was no myometrial invasion, no lymphovascular space involvement, and peritoneal cytology was negative. No adjuvant treatment was required and the patient was followed up every six months. Two years after the surgery, the patient was admitted to hospital for anorexia, loss of weight, asthenia, and severe cough. Computed tomography scan showed disseminated metastasis in the liver, peritoneum, and pulmonary lymphangitis. Ca 125 levels were high at 432 kU/l. Biopsy cores of peritoneum were in favour of metastasis of the previous adenocarcinoma. The patient was referred to the oncology center to initiate chemotherapy with carboplatin + paclitaxel.
Keywords
Endometrioid carcinoma
Gynaecological malingnancy
Peritoneal met
Endometrial cancer
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