IMR Press / EJGO / Volume 39 / Issue 2 / DOI: 10.12892/ejgo3611.2018

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Case Report
Occult breast cancer presenting as a mediastinal mass: case report and review of the literature
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1 Department of Breast Disease, Beijing Shijitan Hospital, Capital Medical University, Beijing, China
2 Department of Pathology, Beijing Shijitan Hospital, Capital Medical University, Beijing, China
3 Department of Surgery, Advocate Christ Medical Center, Advocate Cancer Institute, Oak Lawn, Illinois, USA
Eur. J. Gynaecol. Oncol. 2018, 39(2), 300–303;
Published: 10 April 2018

Occult breast cancer (OBC) is an uncommon diagnosis in clinical practice, mostly presenting with palpable, ipsilateral axillary lymph node metastases. Occasionally, the initial finding is that of distant metastatic disease, with no evidence of a primary breast lesion on clinical examination or other radiographic study. Subsequent pathologic evaluation of the secondary metastatic site will confirm the origin as a primary breast cancer. Here, the authors report a middle-aged woman diagnosed with an OBC that presented with a mediastinal mass. This was later confirmed to represent metastatic breast cancer, with the patient receiving combination chemotherapy and herceptinbased therapy. Breast MRI at 14 months follow-up was unremarkable, supporting the diagnosis of OBC.
Breast cancer
Occult breast cancer
Unknown primary lesion
Metastatic breast cancer
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