IMR Press / EJGO / Volume 39 / Issue 1 / DOI: 10.12892/ejgo3898.2018

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Original Research
Prevalence of pulmonary embolism in gynecological cancer: the experience of a single tertiary center in Okinawa, Japan
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1 Departments of Obstetrics and Gynecology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan
Eur. J. Gynaecol. Oncol. 2018, 39(1), 44–48; https://doi.org/10.12892/ejgo3898.2018
Published: 10 February 2018
Abstract

Purpose: To explore the incidence and outcome of pulmonary embolism (PE) cases in Japanese patients with gynecological malignancy. Materials and Methods: The authors reviewed the medical charts of all patients with gynecological malignancy who had a diagnosis of PE at this Hospital between January 2008 and December 2013. Results: Twenty patients developed PE during the study period. Nineteen patients had advanced or recurrent cancer. The incidence of PE was 1.8%, and those with ovarian, cervical, uterine corpus, and vulvar cancers were 7.5%, 0.86%, 1.0%, and 7.7%, respectively. PE developed in 12 patients before cancer treatment, six during chemotherapy, and two postoperatively. Three patients died as a result of PE. Conclusion: PE more frequently occurred in patients with ovarian and vulvar cancers, and those with advanced/recurrent disease. Patients with active gynecological cancer require thromboprophylaxis throughout hospitalization and not just in the perioperative period, and should be periodically assessed for venous thromboembolism risk.
Keywords
Pulmonary embolism
Deep vein thrombosis
Gynecological cancer
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