IMR Press / EJGO / Volume 38 / Issue 2 / DOI: 10.12892/ejgo3554.2017

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Case Report
Chemotherapy-induced differentiation to cure botryoid rhabdomyosarcoma: a case report and review of the literature
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1 Department of Hematology-Oncology, Hotel-Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon
2 Department of Obstetrics and Gynecology, Hotel-Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon
3 Department of Pathology, Hotel-Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon
4 Department of Radiology, Hotel-Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon
Eur. J. Gynaecol. Oncol. 2017, 38(2), 323–325; https://doi.org/10.12892/ejgo3554.2017
Published: 10 April 2017
Abstract

Rhabdomyosarcoma (RMS) occurs rarely in adults and constitutes 2-6% of all uterine neoplasms. The authors report the case of a 26-year-old woman diagnosed with botryoid RMS that presented discordant progression results on follow up imaging and cytodifferentiation on pathologic control. This case showed that radiological evaluation could be misleading as the tumor demonstrated chemotherapy-induced differentiation without volume reduction. This case illustrates the limitations of using the imaging anatomical dimensions of sarcomas for treatment planning and highlights the potential role of functional imaging to assess the response to treatment.
Keywords
Chemotherapy
Botryoid rhabdomyosarcoma
Cervix
Cytodifferentiation
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