IMR Press / EJGO / Volume 37 / Issue 5 / DOI: 10.12892/ejgo3195.2016

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Case Report
Mayer-Rokitansky-Kuster-Hauser syndrome accompanied by invasive ductal carcinoma: a case report
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1 Department of Obstetrics and Gynecology, Sifa University School of Medicine, Izmir, Turkey Turkey
2 Department of Radiology, Sifa University School of Medicine, Izmir, Turkey
3 Department of Patology, Sifa University School of Medicine, Izmir, Turkey
Eur. J. Gynaecol. Oncol. 2016, 37(5), 744–746;
Published: 10 October 2016

Müllerian agenesis and the absence of organs of Müllerian canal origin are referred to as Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome. Invasive ductal carcinoma constitutes 47-75% of all breast carcinomas and is the most common type. The authors report the first case of invasive ductal carcinoma associated with MRKH syndrome in the literature to their knowledge. A 25-year-old woman with a palpable mass in her right breast for three months presented to the presented clinic. On physical examination a mobile, firm mass measuring 2×2 cm was detected in right breast, at a region close to axilla. A fine needle aspiration biopsy from the lesion revealed malignant cells and thus a segmental mastectomy operation was performed. All genital tract and endocrinological system should be thoroughly examined before administering hormone replacement therapy to patients presenting with primary amenorrhea.The co-occurrence MRKH syndrome of with invasive ductal carcinoma is regarded as coincidental. Confirming the absence of a common etiology, however, requires further genetic studies.
Mayer-Rokitansky-Kuster-Hauser syndrome
Invasive ductal carcinoma
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