IMR Press / EJGO / Volume 37 / Issue 2 / DOI: 10.12892/ejgo2818.2016

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Original Research
Accuracy of intra-operative frozen section and its role in the diagnostic evaluation of ovarian tumors
Show Less
1 Department of Gynaecology, First Affiliated Hospital of Xinjiang Medical University, Urumqi, China
2 The encoding room of medical record department, First Affiliated Hospital of Xinjiang Medical University, Urumqi, China
Eur. J. Gynaecol. Oncol. 2016, 37(2), 216–220;
Published: 10 April 2016

Objective: This retrospective study was undertaken to evaluate the accuracy and role of intra-operative frozen section in the diagnosis of ovarian tumors. Materials and Methods: Retrospective study of 804 ovarian frozen section results between June 2010 and June 2014 was examined to determine the accuracy of frozen section diagnosis. The intra-operative frozen section diagnosis was compared with the permanent (paraffin) section and the overall accuracy, sensitivity, specificity, and positive and negative predictive values of the frozen section were studied. Results: The overall accuracy to determine the status of malignancy was 92.6%. There were 38 (7.4%) false negative and no false positive frozen section diagnoses.The sensitivity, specificity, and positive predictive and negative predictive values for benign ovarian tumors were 100.0%, 97.0%, 91.3%, and 100.0%, respectively; for borderline tumors they were 64.3%, 97.0%, 91.5%, and 94.0%, respectively, and for malignant tumors they were 90.0%, 100.0%, 100.0%, and 85.5%, respectively. Conclusion: This study concluded that frozen section appears to be an adequate technique for the histopathological diagnosis of ovarian tumors, with some limitations observed among borderline and mucinous tumors.
Intra-operative frozen section
Permanent (paraffin) section
Ovarian tumors
Back to top