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European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Primary melanoma of the vagina: a case report and review of literature
A. Stefanović Stefanović1,3, J. Jeremić Jeremić2,3, K. Jeremić Jeremić1,3,*, I. Likić Likić1,3, M. Mitrović Mitrović1,3, J. Stojnić Stojnić1,3
1 Clinic for Obstetrics and Gynecology, Clinical Center of Serbia, Belgrade
2 Clinic for Burns, Plastic and Reconstructive Surgery, Clinical Center Serbia, Belgrade
3 School of Medicine, Belgrade University, Belgrade (Serbia)
Eur. J. Gynaecol. Oncol. 2015, 36(6), 755–757; https://doi.org/10.12892/ejgo2726.2015
Published: 10 December 2015
Primary melanoma of the vagina is a rare and very aggressive tumor with an incidence of only 0.46 per one million women per year and less than 250 cases reported in the literature. Here the authors present a case of a 60-year-old woman, gravida 5, para 5, postmenopausal by 28 years, admitted to the Clinic for Obstetrics and Gynecology, with recurrent vaginal bleeding for the last year and with the complaint of a palpable tumor near the vaginal introitus. The preoperative biopsy revealed melanoma. CT scan did not prove she had distant metastasis. The patient was treated surgically, with wide local excision of four x five cm measured lesion and safety margins of two cm. Bilateral inguinal lymphadenectomy was performed. Follow-up five months after initial diagnosis, revealed no evidence of local recurrency or distant metastasis.