IMR Press / EJGO / Volume 36 / Issue 5 / DOI: 10.12892/ejgo2665.2015

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Case Report
Granular cells tumor of the vulva: an exceptional entity
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1 Gynecological Oncology Unit, La Paz University Hospital, Madrid (Spain)
Eur. J. Gynaecol. Oncol. 2015, 36(5), 605–606;
Published: 10 October 2015

Introduction: Granular cells tumor (GCT) is a rare tumor that develops on skin and soft tissues. Only 1-2% of these tumors present malignant behavior. Material and methods: The authors report three cases of GCT and review the management of these tumors. Case report: The first case is a 73-year-old woman who was diagnosed with an atypical GCT. She was treated with local excision and then presented a local recurrence 21 months after the surgery. The other two cases are 60- and 58-year-old women diagnosed with a benign GCT. They were treated with single excision; both patients underwent second surgery due to margin affectation. Conclusions: Management of GCT is not clear nowadays. The careful selection of patients with poor prognostic factors is very important. Follow-up for early diagnosis of local recurrence and metastases of these tumors is of utmost importance.
Vulvar cancer
Granular cells tumor
S-100 protein
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