IMR Press / EJGO / Volume 36 / Issue 3 / DOI: 10.12892/ejgo2255.2015

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Original Research
Prognostic factors for survival in cervical cancer patients with bone metastasis
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1 Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka (Japan)
2 Department of Radiation Oncology, Osaka University Graduate School of Medicine, Suita, Osaka (Japan)
3 Department of Biomedical Statitics Osaka University Graduate School of Medicine, Suita, Osaka (Japan)
Eur. J. Gynaecol. Oncol. 2015, 36(3), 290–293; https://doi.org/10.12892/ejgo2255.2015
Published: 10 June 2015
Abstract

Purpose: To investigate the prognostic factors for survival in uterine cervical cancer patients who developed bone metastasis. Materials and Methods: Cervical cancer patients with bone metastasis who were treated at the present institute from April 1996 to September 2010 were identified from the authors’ institutional tumor registries. Primary disease, follow-up, and recurrence data were collected and retrospectively reviewed. Univariate and multivariate analyses of prognostic factors for survival were performed. Results: A total of 37 patients that developed cervical cancer bone metastasis were included in the authors’ database. The median survival time after recurrence was 12 months. Univariate analysis revealed that patients with a disease-free interval (DFI) of ten months or less achieved significantly shorter survival after bone metastasis detection than those with a DFI of 11 months or more (median: 8.5 months versus 17 months, p < 0.0001). Multivariate analysis also showed that DFI of ten months or less was a significant predictor of short survival (p = 0.0018). Conclusions: The DFI was found to be independent prognostic factors for survival in cervical cancer patients who developed bone metastasis.
Keywords
Bone metastasis
Cervical cancer
Prognostic factors
Survival
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