IMR Press / EJGO / Volume 35 / Issue 6 / DOI: 10.12892/ejgo25312014

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Original Research
Can adenocarcinoma in situ of the uterine cervix be treated safely by conisation in combination with endocervical curettage?
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1 Department of Gynaecology, University Hospital of Aarhus, Aarhus V (Denmark)
Eur. J. Gynaecol. Oncol. 2014, 35(6), 683–687;
Published: 10 December 2014

Objective: To evaluate the prognostic value of endocervical curettage (ECC) after conisation in patients treated for adenocarcinoma in situ (AIS) of the uterine cervix. Materials and Methods: Patients with AIS diagnosed between 1990 and 2010 and with a minimum of 1.5 years of follow-up were retrospectively identified using computerised clinical files. Results: The authors identified 195 patients (median age 32 years) with a median follow-up of 6.4 years. ECC was performed in 165 patients. In 144 (87%) the initial ECC was normal. In 129 no recurrence was observed during follow-up (90%). A positive ECC was observed in 21. Thirteen patients had hysterectomies; six hysterectomies were normal. Eight patients treated conservatively developed no recurrent disease. Two patients with a positive ECC did not have a hysterectomy and developed recurrent disease. In patients with affected margins, 17% developed recurrent disease. Conclusion: ECC performed during initial conisation is a prognostic tool for the treatment of AIS. Close follow-up is recommended in patients treated conservatively.
Adenocarcinoma in situ
Endocervical Curettage
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