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Case Report
Multifocal microinvasive squamous cell carcinoma with extensive spread of squamous cell carcinoma in situ (CIS) into the uterine corpus, vagina, and left salpinx diagnosed five years after conization of cervical CIS
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1
Department of Obstetrics and Gynecology, Konkuk University Hospital, Konkuk University School of Medicine, Seoul
2
Department of Pathology, Konkuk University Hospital, Konkuk University School of Medicine, Seoul (Korea)
Eur. J. Gynaecol. Oncol. 2014, 35(5), 600–603;
https://doi.org/10.12892/ejgo25092014
Published: 10 October 2014
Abstract
Background: Multifocal microinvasive squamous cell carcinoma (SCC) with extensive spread of squamous cell carcinoma in situ (CIS) into the uterine corpus, salpinx, and vagina is extremely unusual. Case: The authors present a case of 69-year-old woman with hydrometra who was found to have multifocal microinvasive SCC in the endometrium. The CIS had spread superficially throughout the entire endometrium up to the fundus, completely replacing the epithelium. The uterine cervix, vaginal surface and left salpingeal mucosa were involved. She had previously undergone conization due to cervical CIS five years prior. The pathologic reports showed clear resection margins at that time. Conclusion: The present case suggests that CIS in the endometrium spread back to the cervix and vagina, although the definite origin of the first CIS was not determined.
Keywords
Uterine cervix
Microinvasion squamous cell carcinoma of the cervix
Squamous cell carcinoma in situ
Superficial spreading squamous cell carcinoma
Endometrium