IMR Press / EJGO / Volume 35 / Issue 3 / DOI: 10.12892/ejgo24402014

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Case Report
Uterine leiomyosarcoma: report of three cases and review of the literature
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1 Department of Medical and Surgical Sciences, Institute of Obstetrics and Gynaecology, University of Foggia, Foggia
2 Department of Surgical Sciences, Division of Obstetrics and Gynaecology, University of Cagliari, Cagliari
3 Department of Gynaecology and Obstetrics, and Pathophysiology of Human Reproduction, University of Naples "Federico II", Naples
4 Department of Obstetrics and Gynaecology, University of Bari, Bari (Italy)
Eur. J. Gynaecol. Oncol. 2014, 35(3), 328–331;
Published: 10 June 2014

This is the report of three cases of unsuspected uterine leiomyosarcoma diagnosed by pathologist after hysteroscopic resection. The literature on this issue has been reviewed. Mesenchymal uterine tumors are rare malignancies, occurring in only 17 per one million women annually. The three most common variants of uterine sarcoma are endometrial stromal sarcoma, leiomyosarcoma, and malignant mixed Mullerian tumour. Less than one percent of women believed to have a leiomyoma actually have a sarcoma at hysterectomy. According to the authors' experience and the available literature reviewed, the removal of the whole myomatosus lesion, even if its appearance suggests a typical submucosal myoma, represents the only method to definitively rule out the presence of sarcomatous tissue.
Operative hysteroscopy
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