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European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Correlation of subclinical HPV infection with genital warts and cervical erosion
1 Fourth Affiliated Hospital of China Medical University, Shenyang
2 First Affiliated Hospital of Dalian Medical University, Dalian
3 Maternal and Child Health Hospital of Qinhuangdao City, Qinhuangdao
4 First Affiliated Hospital of China Medical University, Shenyang (China)
Eur. J. Gynaecol. Oncol. 2013, 34(5), 462–465;
Published: 10 October 2013
Objective: To investigate the correlation of subclinical human papillomavirus (HPV) infection (SPI) with genital warts and cervical erosion. Materials and Methods: The questionnaire was firstly conducted in experimental groups (genital warts + cervical erosion), and then cervical liquid-based cytology was performed, followed by colposcopy and pathological diagnosis. In the control group, cervical liquid-based cytology and pathological diagnosis were performed. Hybrid Capture 2 assay (HC2) was conducted to detect the cervical high-risk HPV DNA. Results: The positive rate of cervical SPI in experimental groups were significantly higher than control group (p< 0.01), and in the genital warts group it was significantly higher than cervical erosion group (p < 0.05). There was no significant difference of SPI positive rate for cervical erosion with different area and degree (p > 0.05). Compared to control group, the detection rates of cervical high-risk HPV DNA in the experimental groups significantly increased (p < 0.01), and the difference between vulvar condyloma and cervical erosion groups was not statistically significant (p < 0.05). The detection rate of high-risk HPV DNA in positive SPI cases was significantly higher than negative SPI cases. Conclusions: Women with genital warts and cervical erosion are high-risk individuals for cervical cancer, and deserve a focused initial and follow-up management.