IMR Press / EJGO / Volume 34 / Issue 4 / pii/1630906360969-698730432

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Original Research
Diagnostic approach and therapeutic management in early-stage endometrial cancer
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1 Department of Obstetrics and Gynecology, Democritus University of Thrace, General Hospital of Alexandroupolis (Greece)
2 Department of Obstetrics and Gynecology, Clinicum Aschaffenburg, Teaching Hospital of University of Würzburg, Würzburg (Germany)
Eur. J. Gynaecol. Oncol. 2013, 34(4), 319–321;
Published: 10 August 2013
Abstract

Objective: The effectiveness of pelvic and para-aortic lymphadenectomy in the morbidity of patients affected by early-stage endometrial carcinoma (EC) is the subject of this study. Study design: Ninety-two cases with endometrial cancer that underwent para-aorticand pelvic lymphadenectomy, from June 1995 to June 2006, were studied and compared with 30 cases of patients with endometrial cancer without lymphadenectomy. Results: According to the results, systematic pelvic and para-aortic lymphadenectomies improved disease-free and overall survival rates among the patients with endometrial cancer. The mean number of removed para-aortic lymph nodes was 19.01 ± 5.88, whereas the mean number of removed iliac lymph nodes was 32.94 ± 6.69. Forty-two and 31 metastatic iliac and paraaortic nodes were found, respectively. No surgery-related deaths and major intraoperative injuries occurred. The frequency and the type of postoperative complications were not affected by the performance of lymphadenectomy. The morbidity rate was 6.2%, similar to the group without lymphadenectomy (5.79%). No recurrence occurred in the group with lymphadenectomy, while in the other group the recurrence rate was 23.3%. Conclusions: Lymph nodes metastases can be observed in early stages of EC. Pelvic and para-aortic lymphadenectomies seems to provide profound information about the Stage of the disease and the patient’s survival, identifying which patients are suitable for supplementary treatment, without significant clinical increase of morbidity.
Keywords
Endometrial cancer
Paraortal iliac lymphadenectomy
Morbidity
Early stages
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