IMR Press / EJGO / Volume 34 / Issue 1 / pii/1630905358825-974383604

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Original Research
Decreased prevalence of high-risk human papillomavirus infection is associated with obesity
Show Less
1 Department of Obstetrics and Gynecology, Konyang University Hospital, Konyang University College of Medicine, Daejon
2 Department of Obstetrics and Gynecology, Hanyang University College of Medicine, Seoul
3 Department of Obstetrics and Gynecology, Sungkyunkwan University School of Medicine, Seoul
4 Dr. Park’s Ob & Gyn Clinic, Seoul (Republic of Korea)
Eur. J. Gynaecol. Oncol. 2013, 34(1), 70–74;
Published: 10 February 2013

Purpose of investigation: Obesity is correlated with low education, low economic status, and lower rates of Pap smears, which are known as socio-demographic risk factors for cervical cancer. However, the association between obesity and high-risk human papillomavirus (HR-HPV) infection, the necessary cause of cervical cancer, and its related precursors, is not established. Materials and Methods: The authors examined the association between obesity and HR-HPV infection in 6,868 patients, who participated in annual health examinations at the Kangbuk Samsung Hospital in Seoul, Korea, from January through December 2007. Results: The prevalence of HR-HPV infection was 14.8%. Women infected with HR-HPV had a lower body mass index (BMI), when compared with non-infected women. After adjustment for alcohol intake, cigarette smoking, and marital status, HR-HPV infection was found to be negatively associated with BMI. When the analysis was stratified according to BMI, the risk of HR-HPV infection was significantly lower among those who were overweight (OR = 0.817, 95% CI = 0.680 – 0.982), or obese (OR = 0.688, 95% CI = 0.556 – 0.851), when compared with women with normal weight. Conclusion: HR-HPV infection was associated with obesity defined by BMI, with a lower prevalence of infection observed in obese women.
Risk factor
Back to top