IMR Press / EJGO / Volume 33 / Issue 5 / pii/1631087399675-77038269

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Original Research
Diagnostic value of thrombocytosis and high CA 125 level in women with adnexal masses
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1 Department of Obstetrics and Gynecology, Near East University Faculty of Medicine, Lefkosa, TRNC, Mersin, Turkey
Eur. J. Gynaecol. Oncol. 2012, 33(5), 517–520;
Published: 10 October 2012
Abstract

Aim: The aim of this study was to determine the diagnostic value of thrombocytosis and high CA 125 levels in women with benign and malign adnexal masses. Thrombocytosis (platelet counts >400 × 10(9)/l) has been identified as a poor prognostic factor in many cancers including certain gynecologic malignant tumors such as endometrial, cervical, and ovarian cancers. Methods: Medical charts of 180 patients with adnexal masses were retrospectively reviewed and analyzed for the association of preoperative thrombocytosis and high CA 125 level with other clinical prognostic factors. Results: Of the 180 participants, 68 (68% of malignant adnexal masses) had thrombocytosis and 74 patients (74% of malignant adnexal masses) had elevated CA 125 levels. The patients with preoperative thrombocytosis were found to have greater elevations of CA 125 levels, more advanced stage disease, and higher grade tumors. Conclusion: Presence of thrombocytosis and high CA 125 alone and in combination may be used as a prognostic factor in the management of women with adnexal masses since they are already used as clinical tests for several purposes.
Keywords
Thrombocytosis
CA125
Adnexal masses
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