IMR Press / EJGO / Volume 33 / Issue 5 / pii/1631087389819-500834910

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Original Research
Evaluation of the histopathological diagnosis of patients preoperatively diagnosed with atypical endometrial hyperplasia after hysterectomy
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1 Izmir Aegean Maternity and Women's Health Hospital, Izmir, Turkey
Eur. J. Gynaecol. Oncol. 2012, 33(5), 459–462;
Published: 10 October 2012

Objective: To evaluate the patients diagnosed with atypical endometrial hyperplasia preoperatively, and compare preoperative and postoperative results. Materials and method: We investigated the files of 58 patients diagnosed with atypical endometrial hyperplasia who were treated surgically after clinical evaluation. We compared sociodemographic diagnosis, preoperative and postoperative diagnosis. Results: Mean-age of patients was 51.7. Obesity, diabetes mellitus, hypertension and infertility were seen, respectively, in eight cases (13.7%), 12 cases (20.6%), 19 cases (32.7%) and four cases (6.8%). While endometrial cancer was not found postoperatively in patients preoperatively diagnosed with simple atypical endometrial hyperplasia, we determined well differentiated endometrial adenocarcinoma in 44.7% of the patients. Conclusion: In the literature the probability of developing well differentiated endometrial cancer from complex atypical endometrial hyperplasia is 40-50%. All patients diagnosed with complex atypical hyperplasia should be evaluated preoperatively for well differentiated adenocarcinoma and undergo an appropriate surgical technique and staging.
Consensus diagnosis
Endometrial hyperplasia
Endometrioid adenocarcinoma
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