IMR Press / EJGO / Volume 33 / Issue 4 / pii/1631087292774-1975646854

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Case Report
“Intestinal-type” mucinous adenocarcinoma of the vulva: a report of two cases
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1 Department of Gynecology, Gynecologic Oncology Unit, Obstetrics and Neonatology (DIGON)
2 Department of Pathology, University of Bari, Bari (Italy)
Eur. J. Gynaecol. Oncol. 2012, 33(4), 433–435;
Published: 10 August 2012
Abstract

Background: “Intestinal-type” mucinous carcinoma of the vulva is extremely rare with very few cases reported in the literature. Case report: The authors report two patients who had diagnosis of intestinal-type mucinous adenocarcinoma of the vulva after excisional biopsy. In both cases, restaging was perfomed with total body computed tomography (CT) scan, gastroscopy, and colonoscopy that showed no other site of disease. A radical vulvectomy with bilateral systematic inguinal lymphadenectomy was performed, and in both cases no residual disease was found. A patient developed metastatic (liver, bone marrow) colonic cancer 36 months after primary surgery, received multiple lines of chemotherapy, and died of disseminated disease 18 months after diagnosis. The other patient was found to have dysplastic polyp in the sigmoid colon, and is alive without disease at 39 months after primary diagnosis. Conclusion: Intestinal-type mucinous carcinoma of the vulva has a poor prognosis. Strict endoscopic follow-up of the colon is mandatory in such cases, considering the high propensity of associated gastrointestinal (GI) tumors.
Keywords
Adenocarcinoma of the vulva
Intestinal-type
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