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European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Long-term disease-free survival in three ovarian cancer patients with a single relapse
C. Y. Chen1, H. P. Chang2, K. K. Ng3, C. C. Wang4, C. H. Lai1, A. Chao1,*
1 Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan
2 Department of Nuclear Medicine, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan
3 Department of Radiology, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan
4 Department of Radiation Oncology, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan (Taiwan)
Eur. J. Gynaecol. Oncol. 2012, 33(3), 321–323;
Published: 10 June 2012
Recurrent ovarian cancer with long-term survival is uncommon and often associated with poor prognosis. We report three cases of patients with advanced ovarian cancer who have achieved long-term disease-free survival following a single prior relapse. Case 1 relapsed with a localized bulky tumor and received a complete surgical resection and chemotherapy. Case 2 had a persistent central pelvic tumor after debulking surgery and second-line chemotherapy, and yet achieved excellent control with concurrent chemoradiation to the true pelvis. Case 3 relapsed with paraaortic lymph node metastasis and probable lung metastasis (subsequently negated by positron emission tomography) and received chemotherapy alone. These three patients have since remained disease-free for 13, 12, and seven years, respectively, since their first relapse. We conclude that select patients can obtain long-term disease-free survival after the first relapse by accurate restaging and aggressive multimodality treatment.