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European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Malignant fibrous histiocytoma of the ovary: a case report
A. Stefanovic1,2,*, J. Stojnic1,2, K. Jeremic1,2, M. Jeftovic2, L. Arsenijevic2, N. Zecevic3J. Atanackovic2
1 Clinic of Obstetrics and Gynecology, Clinical Center of Serbia
2 Medical School, University of Belgrade
3 Clinic of Obstetrics and Gynecology “Narodni front”, Belgrade (Serbia)
Eur. J. Gynaecol. Oncol. 2012, 33(2), 236–239;
Published: 10 April 2012
Malignant fibrous histiocytoma (MFH) is the most common soft-tissue sarcoma of late adult life occurring predominantly in the extremities and the retroperitoneum. MFH of the ovary is very rare, with only six cases previously reported. A 67-year-old woman with a right pelvic tumor highly suspicious of ovarian carcinoma was submitted to exploratory laparotomy. Total abdominal hysterectomy, bilateral salpingo-oophorectomy, total omentectomy, pelvic and paraaortic lymphadenectomy with right hemicolectomy along with permanent cutaneous ileostomy were performed. Since a storiform-pleomorphic type of MHF was diagnosed from histopathological and immunohistochemical findings, chemotherapy was proposed as the postoperative treatment. Despite extensive surgery with negative surgical margins, the patient had recurrence of the tumor within four months, and was submitted to secondary surgery. A combination of chemo- and radiotherapy was performed postoperatively, but the patient developed respiratory problems and died one year later from the primary diagnosis.
Malignant fibrous histiocytoma