IMR Press / EJGO / Volume 33 / Issue 1 / pii/1631086195402-131141129

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Original Research
Combination of fertility preservation strategies in young women with recently diagnosed cancer
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1 Department of Obstetrics and Gynecology, Brno University Hospital and Masaryk University School of Medicine, Brno (Czech Republic)
2 Department of Internal Medicine and Hematooncology, Brno University Hospital and Masaryk University School of Medicine, Brno (Czech Republic)
Eur. J. Gynaecol. Oncol. 2012, 33(1), 42–50;
Published: 10 February 2012
Abstract

Background/Aims: The study describes clinical management and outcomes of currently available fertility preservation techniques in a set of 154 young female cancer patients. Methods: Patients in reproductive age with newly diagnosed cancer were offered embryo or oocyte cryopreservation, ovarian tissue cryopreservation and the administration of GnRH analogues during chemotherapy. Particular attention was given to the technical aspects and clinical application of these fertility preservation techniques. Results: During the study period (2004-2009), 154 young female cancer patients were offered fertility preservation counseling. Patient’s average age was 29.4 years and average parity was 0.7 children. Administration of GnRH analogues (n = 123, 79.9%) and ovarian tissue cryopreservation (n = 15, 9.7%) were the most commonly used fertility preservation strategies. In 20 cases (16.1%), the combination of several fertility preservation techniques was offered to individually selected patients. Conclusions: Combination of fertility preservation techniques gives young cancer patients the best chance for future fertility and should be concentrated in specialized centers.
Keywords
Cancer
infertility
Fertility preservation
Oocyte cryopreservation
Ovarian tissue cryopreservation
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