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European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Comparison of nerve content in removed parametrial tissue after classic radical hysterectomy and nerve-sparing radical hysterectomy - histologic evaluation
1 Department of Obstetrics and Gynecology, University Medical Centre Ljubljana, Ljubljana (Slovenia)
2 Department of Obstetrics and Gynecology, S. Anna Hospital, Reggio Emilia Local Health Unit, Castelnovo ne Monti (Italy)
Eur. J. Gynaecol. Oncol. 2012, 33(1), 21–24;
Published: 10 February 2012
Purpose of investigation: The aim of this study was to find whether nerve-sparing radical hysterectomy resulted in a lower amount of nerves in the removed parametrial tissue. Methods: Histological specimens from nerve-sparing radical hysterectomy (28 cases) were compared with those obtained after classic radical hysterectomy (26 cases). Width of the parametria and vaginal cuff were measured. Using a point counting technique, nerve areal density was determined in cross sections of resected parametria at 0.5 cm (A), 1 cm (B), 1.5 cm (C) from the cervix. Results: The width of the resected parametria was smaller in the study group (right side p < 0.013; left side; p < 0.011). The nerve areal density in the lateral part of the right parametrium was lower in the study group (p < 0.01) (Student’s t-test). Conclusion: Modified radical hysterectomy is less radical and is nerve-sparing.
Nerve-sparing radical hysterectomy
Parametrial nerve areal density
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