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Cite this article
A rare ovarian Leydig cell tumor (hilar type) causing virilization in a postmenopausal woman
1 Pathology Department and 22nd Department of Obstetrics and Gynecology Aretaieion University Hospital, University of Athens (Greece)
Eur. J. Gynaecol. Oncol. 2011, 32(5), 557–559;
Published: 10 October 2011
All patients with virilization signs, increased levels of androgen hormones and rapidly progressive hirsutism should be evaluated for an androgen-producing tumor. The ovarian origin of virilization can be suspected by the presence of elevated levels of circulating androgens, with normal levels of cortisol metabolites and a negative dexamethasone suppression test. A case report of a 50-yearold postmenopausal patient with rapidly progressive hirsutism is presented. After an extensive preoperative investigation a right oophorectomy was performed and a Leydig-hilus cell tumor was diagnosed.
Sex cord-stromal tumors