IMR Press / EJGO / Volume 32 / Issue 5 / pii/1630980908874-1796130607

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Case Report
An extremely rare presentation of relapse in endometrioid endometrial adenocarcinoma: isolated metastases to the tibia and humerus. Case report and review of the literature
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1 Palliative Care Unit, Chair of Oncology, Medical University of Lodz
2 Department of Palliative Medicine, Regional Cancer Center, Copernicus Memorial Hospital of Lodz
3 Gynaecological Cancer Outpatient Clinic, Regional Cancer Center, Copernicus Memorial Hospital of Lodz
4 Department of Pathology, Chair of Oncology, Medical University of Lodz, Lodz (Poland)
Eur. J. Gynaecol. Oncol. 2011, 32(5), 547–550;
Published: 10 October 2011

In endometrial carcinoma patients, metastases to bones are rare and isolated metastases to extremities are extremely rare. We describe the case of a 59-year-old patient who underwent surgery followed by adjuvant radiotherapy due to endometrioid endometrial adenocarcinoma (grade 2, FIGO Stage II). After intervals of nine and 18 months respectively, she was diagnosed with metastatic tumours located in the right tibia and in the left humerus. The metastases were confirmed by biopsy. Following irradiation of metastatic lesions, the relief of symptoms was observed, and the patient remains under observation. We conclude that patients presenting a history of endometrial carcinoma with chronic pain in the extremities should be carefully evaluated, because although extremely rare, the carcinoma can metastasize to bones. Treatment of bone metastasis from endometrioid endometrial carcinoma by irradiation may increase quality of life and prolong survival.
Endometrial carcinoma
Bone extremities
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