IMR Press / EJGO / Volume 32 / Issue 2 / pii/1630979935097-2136307375

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Case Report
Alveolar rhabdomyosarcoma originating from the uterine cervix
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1 Division of Medical Oncology, Tulay Aktas Oncology Hospital, School of Medicine, Ege University
2 Division of Internal Medicine, School of Medicine, Ege University, Bornova, Izmir (Turkey)
Eur. J. Gynaecol. Oncol. 2011, 32(2), 196–198;
Published: 10 April 2011

Cervical alveolar rhabdomyosarcoma is a rare condition associated with poor prognosis. An 18-year-old patient presented with vaginal bleeding and a protruding mass from the vagina. Biopsy of the mass revealed alveoler rhabdomyosarcoma (ARMS), and radiological evaluation demonstrated that it originated from the uterine cervix. First, Wertheim’s operation was carried out followed by four cycles of vincristine, actinomycine-D, ifosfamide (VAI) chemotherapy. However, the disease relapsed within three months, and the patient died of disease progression. Despite combination treatment, we could not achieve a desirable survival advantage in ARMS. Future studies may unveil the genomic profile of this rare condition, leading to invention of targeted therapies, which is the emerging trend in the treatment of sarcomas.
Alveolar rhabdomyosarcoma
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