IMR Press / EJGO / Volume 32 / Issue 1 / pii/1630982574832-944195512

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Case Report
Fibula metastasis as the presenting feature of vaginal cancer
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1 Department of Gynecology and Gynecologic Oncology
2 Department of Orthopedic Surgery, Universitair Ziekenhuis Antwerpen (Belgium)
Eur. J. Gynaecol. Oncol. 2011, 32(1), 114–116;
Published: 10 February 2011

Background: Metastatic bone involvement in vaginal carcinoma has not been reported in the literature. Case: A 74-year-old woman was referred for a painful fibula to the orthopedic surgeon. A work-up revealed an isolated metastatic bone lesion in the right fibula of a primary squamous carcinoma of the vagina. Rather surprisingly this lesion had been missed during all previously regular clinical gynecological examinations. Palliative therapy including bone resection and radiotherapy of the metastatic lesion were given. Conclusion: This case highlights: (1) the unique presentation of a vaginal cancer by pain in the lower leg secondary to a metastasis in the fibula; (2) that a speculum examination can mask a mid-vaginal lesion; (3) the importance of aggressive treatment of a solitary bone metastasis in order to provide effective palliation.
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