IMR Press / EJGO / Volume 31 / Issue 5 / pii/1630985437968-223190778

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Original Research
Isolated groin recurrence in vulval squamous cell cancer (VSCC). The importance of node count
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1 Royal Marsden Hospital Department of Gynaecological Oncology, London
2 West London Gynaecological Cancer Centre, Imperial College, London
3 Institute of Cancer Research, Sutton (UK)
Eur. J. Gynaecol. Oncol. 2010, 31(5), 510–513;
Published: 10 October 2010
Abstract

Objective: To determine whether there is a node count which can define an adequate inguinofemoral lymphadenectomy (IFL) in primary VSCC. Methods: A retrospective and prospective review of patients with node negative VSCC who had a full staging IFL. Detection of isolated groin recurrences (IGR) would allow groins with higher risk of groin recurrence to be identified. Results: The median node count of 228 IFLs in 139 patients was eight (0-24). There were six IGR (4.3%). Increased rate of IGR was present in patients with increased age, tumour diameter and depth of invasion, lymphovascular space invasion, unilateral IFL, and moderate/poor tumour grade. In the 138 groins with node counts of eight or greater there were no IGRs compared to six in the patients with either undissected groins or groin node counts less than eight (p = 0.030) Interval to IGR was significantly shorter than other sites of recurrence. Both disease-specific and overall survival were significantly reduced in IGR. Conclusions: An inadequate IFL is a nodal count of less than eight per groin; both these groins and undissected groins are at increased risk of IGR and should have close surveillance.
Keywords
Vulval Cancer
Node count
Lymphadenectomy
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