IMR Press / EJGO / Volume 31 / Issue 1 / pii/1630984347588-481969504

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Case Report
Immunohistochemical findings in primary fallopian tube cancer. Case report
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1 Department of Obstetrics and Gynecology, Provincial Hospital, Przemysl
2 Department of Perinatology, Medical University of Bialystok, Bialystok
3 Department of Medical Pathomorphology, Medical University of Bialystok, Bialystok (Poland)
Eur. J. Gynaecol. Oncol. 2010, 31(1), 120–122;
Published: 10 February 2010
Abstract

Primary fallopian tube carcinoma is a rare malignancy, representing about 1% of female genital tract malignancies. We present a case report and compare the medical performance with accessible data from the literature as well as present immunohistochemical analysis of estrogen, progesterone, and proliferative together with basic cytokeratin reactions. We found that immunohistochemical expression of ER-β was dominant over ER-α which encourages further evaluations to be performed on a larger number of samples, especially taking into account the very scant progesterone receptor expression we noted. On the basis of the course of disease under study, etiological problems and the possibility of clinical misdiagnosis have been discussed. The low prevalence rate and lack of clear symptoms of this type of carcinoma makes the final clinical diagnosis almost impossible without an intraoperative histopathological study. Multicenter studies are needed to improve the understanding of possible risk factors.
Keywords
Primary fallopian tube cancer
Oncogenes
ERα
ERβ
CK7
CK20
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