IMR Press / EJGO / Volume 30 / Issue 4 / pii/2009114

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Case Report

Paget’s disease of the vulva in a patient with scleroderma and underlying adenocarcinoma: case report

Show Less
1 First Department of Internal Medicine, AHEPA University Hospital, Thessaloniki (Greece)
Eur. J. Gynaecol. Oncol. 2009, 30(4), 458–459;
Published: 10 August 2009
Abstract

Systemic sclerosis (SSc) is a multisystem connective tissue disease characterized by fibrosis of the skin and internal organs. Several studies have demonstrated an increased frequency of cancer in patients with SSc. We report a case of a 71-year-old woman with SSc, who presented with an eczematous lesion of the vulva. The diagnosis of Paget’s disease of the vulva (PVD) was established. The patient underwent radical vulvectomy, but 18 months later died due to adenocarcinoma of unknown primary origin. SSc and PVD are associated with various types of malignancies and patients suffering from these diseases should be under surveillance in order for any suspicious symptoms of malignancy to be early detected and investigated. 

Keywords
Paget’s disease of the vulva
Scleroderma
Malignancy
Share
Back to top