IMR Press / EJGO / Volume 30 / Issue 2 / pii/2009039

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Original Research

Metastatic involvement of the urinary tract in patients with advanced ovarian carcinoma: lessons from the autopsy for an interdisciplinary treatment approach

Show Less
1 Department of Urology, University Hospital Basel (UHB)
2 Department of Gynecology and Obstetrics, UHB
3 Institute of Pathology, University of Basel, Basel
4 Institute of Pathology, Cantonal Hospital Baden, Baden
5 JPS Institute for Biomathematics, Basel (Switzerland)
Eur. J. Gynaecol. Oncol. 2009, 30(2), 174–177;
Published: 10 April 2009

Purpose of investigation: Frequency and extent of metastases in urologic organs found at autopsy of ovarian carcinoma patients were evaluated. Methods: Autopsy reports from 170 patients who died of advanced ovarian carcinoma between 1975 and 2005 were studied. The distribution of abdominal metastatic sites with particular attention to the involvement of the urologic organs, and hydronephrosis was analyzed. Results: The distribution of metastatic sites was as follows: kidney (n = 6, 3.5%), urinary bladder (n = 38, 22.4%), and ureter (n = 20, 11.8%). In 36 patients, hydronephrosis was observed (21.2 %); of these patients, 20 (55.6%) also had ureteral involvement. All patients with ureteral involvement had hydronephrosis. Conclusion: Hydronephrosis in late stages of ovarian carcinoma, usually attributed to extrinsic compression of the ureter by an abdominal tumor, may also be explained by ureteral metastases. This fact must be considered in the clinical management of these patients, particularly in the restoration of luminal patency through an endoscopically placed internal ureteral stent.

Ovarian cancer
Urinary tract
Back to top