IMR Press / EJGO / Volume 30 / Issue 1 / pii/2009015

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Original Research

Clinicopathologic analysis: relationship between endometrial carcinoma and uninvolved endometrium

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1 Department of Gynecology & Obstetrics, Haseki Training & Research Hospital, Ilstanbul (Turkey)
2 Department of Pathology, Haseki Training & Research Hospital, Ilstanbul (Turkey)
Eur. J. Gynaecol. Oncol. 2009, 30(1), 71–74;
Published: 10 February 2009

Objective: The aim of this study was to compare the histopathologic features and surgical stage of endometrial carcinoma with tumor-free endometrial tissues. Methods: Data from the files of 80 patients with endometrial carcinoma who were managed at Haseki Training & Research Hospital between January 2001 and July 2007 were evaluated. We assessed tumor-free endometrium, stage, histologic type and grade, depth of myometrial invasion, peritoneal cytology, adnexal-cervical involvement, lymphovascular space invasion (LVSI), and lymph node metastases. Results: Twenty-nine patients (43%) with endometrial carcinoma had concomitant endometrial hyperplasia. Seven patients (10%) had one or more areas of metaplasia in the endometrium adjacent to the carcinoma. Endometrial carcinoma with atrophic background was significantly associated with aggressive histopathologic type (p < 0.04) and LVSI (p < 0.02). Conclusion: The histological characteristics of non-tumoral endometrium were found to be critical in determining the type of aggressive tumor and LVSI in atrophy-associated carcinomas.

Endometrial carcinoma
Tumor-free endometrium
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