IMR Press / EJGO / Volume 29 / Issue 5 / pii/1631004271804-1334599341

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Case Report
Malignant transformation of uterine leiomyomata
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1 Department of Surgical Sciences, Institution of Obstetrics and Gynecology, University of Foggia
2 Service of Echography, Casa di Cura Dott. Marchetti, Macerata
3 Department of Gynecology, Perinatology and Child Welfare, II Faculty of Medicine and Surgery, “La Sapienza” University of Rome (Italy)
Eur. J. Gynaecol. Oncol. 2008, 29(5), 543–544;
Published: 10 October 2008

The malignant transformation of a uterine leiomyoma is still debated and, if it occurs, it is very rare. The case of a patient affected by three small leiomyomas, monitored by the same gynecologist over the years is described. Two of these leiomyomas were transformed into leiomyosarcoma after menopause and the patient died despite receiving therapy. The case reported here is meant to underline the need to keep all uterine myomas in check since the transition into leiomyosarcomas may occur with an evolution over a time period which has not been established so far.
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