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Carcinosarcoma of the uterus: a case report and review of the literature
E. Spaziani1, M. Picchio2,*, V. Petrozza3, M. Briganti4, F. Ceci2, A. Di Filippo1, B. Sardella3, F. De Angelis1, C. Della Rocca3, F. Stagnitti1
1 Medicine and Surgery, “A. Fiorini” Hospital, University of Rome “La Sapienza”, Polo Pontino
2 A. S. L. Latina, Surgery Unit “A. Fiorini” Hospital, Terracina
3 Department of Experimental Medicine, Medicine and Surgery, University of Rome “La Sapienza”, Polo Pontino
4 A. S. L. Latina, Radiology Unit, “A. Fiorini” Hospital, Terracina (Italy)
Eur. J. Gynaecol. Oncol. 2008, 29(5), 531–534;
Published: 10 October 2008
Carcinosarcoma is a rare tumor of the uterus with a poor prognosis. We present a case of uterine carcinosarcoma in an 82-yearold woman who suffered from pervaginal bleeding for ten months duration with progressive anemia. Abdominopelvic nuclear magnetic resonance (NMR) imaging showed the presence of an intrauterine mass, infiltrating the myometrium and reaching the cervix. The patient was submitted to total abdominal hysterectomy with bilateral salpingo-oophorectomy. The carcinosarcoma, arising from the lumen of the uterus, infiltrated the inner one-third of the myometrial layer (pT1b, pNx, pMx; FIGO Stage 1B). A CT of the total body performed six months after surgery showed no signs of recurrent and/or metastatic tumor. The clinicopathological features, treatment options and prognosis of this aggressive neoplasm are reviewed.