IMR Press / EJGO / Volume 29 / Issue 5 / pii/1631004268423-1298296076

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Case Report
Primary squamous cell carcinoma of the endometrium: a case report
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1 Division of Gynecologic Oncology, Department of Surgery, Roswell Park Cancer Institute, Buffalo, NY
2 Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (USA)
Eur. J. Gynaecol. Oncol. 2008, 29(5), 527–530;
Published: 10 October 2008
Abstract

Purpose of investigation: Primary squamous cell carcinoma of the endometrium (PSCCE) is an extremely rare entity. Methods: We present the clinical and pathological findings of a 90-year-old patient with International Federation of Gynecologists and Obstetricians Stage 1C primary squamous cell carcinoma of the endometrium who was treated with hysterectomy and bilateral salpingooophorectomy. Results: The patient declined adjuvant therapy and continues on progestin therapy. She was free of disease at a oneyear follow-up visit. In addition, the current literature is discussed in this report. Conclusions: Since primary squamous cell carcinoma of the endometrium is so infrequent, it is difficult to evaluate the efficacy of adjuvant therapy. Although the prognosis historically has been reported as poor compared to endometrial adenocarcinoma, the prognosis does seem to be dependent on the surgical stage at diagnosis rather than on the adjuvant treatment component.
Keywords
Endometrial cancer
Squamous epithelium
Primary squamous cell carcinoma of the endometrium
HPV
Treatment
Follow-up
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