IMR Press / EJGO / Volume 28 / Issue 3 / pii/2007158

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Case Report

Androgenic juvenile granulosa cell tumor of the ovary with cystic presentation: a case report

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1 Research Institute of Oncology (IPON)/Discipline of Gynecology and Obstetrics, Brazil
2 Discipline of Special Pathology, Federal University of Triangulo Mineiro (UFTM), Uberaba-MG, Brazil
Eur. J. Gynaecol. Oncol. 2007, 28(3), 236–238;
Published: 10 June 2007
Abstract

Granulosa cell tumors account for approximately 1-2% of all ovarian tumors. There are two types: adult granulosa cell tumor and juvenile granulosa cell tumor. Juvenile granulosa cell tumors constitute 5% of this histological subtype, and the prognosis is good because the majority present as Stage I tumors. The treatment can consist of conservative surgery. Androgen production is rare and produces virilization in women. These tumors are usually solid or predominantly solid. We describe the case of a 13-year-old girl with androgenic manifestations and increased abdominal size. Her plasn_ia testosterone level was elevated. A left adnexal cyst (14.4 x 9.1 x 9.7 cm) was revealed at pelvic ultrasonography. The patient underwent an exploratory laparotomy, revealing a left ovarian cystic tumor. Diagnosis was juvenile granulosa cell tumor.

Keywords
Granulosa cell tumor
Adolescent
Testosterone
Ovarian Neoplasms
Hyperandrogenism
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