IMR Press / EJGO / Volume 28 / Issue 3 / pii/2007146

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Original Research

Prediction of myometrial invasion in patients with endometrial carcinoma: Comparison of magnetic resonance imaging, transvaginal ultrasonography, and gross visual inspection

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1 Department of Obstetrics & Gynecology, School of Medicine, Niigata University, Niigata, Japan
Eur. J. Gynaecol. Oncol. 2007, 28(3), 193–195;
Published: 10 June 2007

This study evaluated the accuracy of magnetic resonance imaging (MRI) and transvaginal ultrasonography (TYUS) m preopera­tive detection of myometrial invasion by endometrial cancer. We also evaluated the results of gross visual inspection (GVI) of sur­gical specimens compared with histopathological diagnosis. One hundred and seventy-seven women underwent preoperative pelvic MRI, TYUS, and intraoperative GVI. Myometrial tumor invasion was evaluated histologically and classified as absent (depth a), superficial (depth b: ≤ 50% invasion), or deep (depth c: > 50% invasion). The accuracy of MRI, TYUS, and GVI were 64.0, 66.9, and 63.8%, respectively. The positive predictive values of of each modality for depth a were 52.6, 51.4, and 52.2%, respectively. The accuracy of each in detecting deep myometrial invasion (depth c) were 84.0, 86.9, 83.1 %. Although evaluation of depth a was limited with all modalities, MRI and TYUS were shown to be reliable for preoperative evaluation of deep myometrial invasion. The high accuracy of these three methods suggests that they are useful either interchangeably or in combination.

Endometrial cancer
Myometrial invasion
Magnetic resonance imaging
Transvaginal ultrasonography
Gross visual inspection
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