IMR Press / EJGO / Volume 27 / Issue 2 / pii/2006128

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Original Research

Definitive and palliative radiotherapy for cervix cancer in the elderly

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1 Departments of Radiology, Louisiana State University Health Sciences Center, Shreveport, LA, USA
2 Obstetrics-Gynecology, Louisiana State University Health Sciences Center, Shreveport, LA, USA
3 Biometry, Louisiana State University Health Sciences Center, Shreveport, LA, USA
Eur. J. Gynaecol. Oncol. 2006, 27(2), 115–118;
Published: 10 April 2006
Abstract

The elderly population is increasing in number. Aggressive therapeutic intervention in this patient group may not always be pos­sible because of age, the presence of co-morbidity, and poor functional status. Hence, individualized management of cervix cancer (CC) in the elderly is often practiced. Because of the preceding consideration, the cases of 79 women 65 years of age and older with CC treated with radiation over the last 20 years were reviewed. The cases were classified into two groups - those who were aggressively irradiated (group 1:43 patients) and those managed less intensively for palliation (group 2:36 patients). Local tumor control, complications, and survival were assessed. There were fewer extremely aged(≥75 years of age) women (p = 0.006) with advanced stage disease (p = 0.012) in group 1 than in group 2. Also, group 1 women experienced fewer treatment failures (p < 0.0003) and more of them were alive and well at last follow-up (p < 0.005) than those from group 2. The median survival periods for groups 1 and 2 were 60 months and 11 months, respectively (p < 0.0001); the corresponding 5-year crude survival rates were 54% and 19%, respectively (p = 0.002). Two women required remedial surgery for bowel obstruction/perforation after irradiation, and one patient sustained chronic radiation cystitis.

Keywords
Uterine cervix
Cancer
Radiotherapy
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