IMR Press / EJGO / Volume 27 / Issue 1 / pii/2006113

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Original Research

Secondary tumors of the intestines in females: A retrospective clinicopathologic study of seven cases

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1 Pathology Laboratory, University of Athens, Aretaieion Hospital, Athens, Greece
2 2nd Clinic of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, Athens, Greece
3 2nd Clinic of Surgery, University of Athens, Aretaieion Hospital, Athens, Greece
Eur. J. Gynaecol. Oncol. 2006, 27(1), 56–60;
Published: 10 February 2006
Abstract

Objective: To investigate the primary site and the pathological features of secondary intestinal tumors in females, with emphasis on their differential diagnosis from primary neoplasms of the intestines. Methods: Seven cases of secondary intestinal tumors in females were retrieved from the archival files of our laboratory. The relative clinical data were also reviewed. Inmmunohistochemistry was performed in cases with diagnostic difficulties. Results: The primary site of the tumor was defined as follows: the ovary (ovarian adenocarcinoma) in five cases (71.4%), the skin (cutaneous malignant melanoma) in one case (14.28%) and the uterine corpus (mixed mullerian tumor) in one case (14.28%). In two cases the primary site was not determined initially, but the investigation showed that the primary tumor was ovarian in origin. In five cases the existence of a primary tumor was already known. Immunohistochemistry was applied in three cases for confirma­tion of the suspected primary tumor by histological examination. Conclusion: Histological diagnosis of secondary intestinal tumors may be extremely difficult, especially when the primary site is not previously known, and because of the tendency of certain secondary tumors to mimic, both grossly and microscopically, the primary ones. Immunohistochemistry is extremely helpful in resolving these diagnostic difficulties.

Keywords
Secondary tumors
Intestines
Ovarian adenocarcinoma
Differential diagnosis
Immunohistochemistry
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