IMR Press / EJGO / Volume 26 / Issue 5 / pii/2005236

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Case Report

Sequential recurrences of ovarian granulosa cell tumour 10 and 11 years after initial diagnosis as haemoperitoneum and subhepatic mass: A case report and review of the literature

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1 3rd Surgical Department, University Hospital “Attikon”, Medical School, University of Athens, Athens (Greece)
2 Department of Pathology, Medical School, University of Athens, Athens (Greece)
Eur. J. Gynaecol. Oncol. 2005, 26(5), 572–576;
Published: 10 October 2005
Abstract

Adult granulosa cell tumours (GCTs) are rare ovarian neoplasms characterised by an indolent course and a propensity for late recurrence. Due to frequent endocrine manifestations most GCTs are diagnosed at an early stage. However, clinical behaviour can not be safely predicted on the basis of conventional clinicopathologic parameters. Surgery remains the cornerstone of therapeutic management. We report on a rare case of a Stage IA GCT twice recurring ten and 11 years after initial surgical treatment. The first recurrence presented as an acute abdomen due to haemoperitoneum after tumour rupture. The second recurrence presented as a subhepatic mass. This case emphasises the need for extended, lifelong follow-up even for patients with early stage, apparently com­pletely removed GCTs. Prognostic parameters and therapeutic options especially for patients with recurrent disease are discussed

Keywords
Granulosa cell tumour
Ovary
Recurrence
Haemoperitoneum
Subhepatic mass
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