IMR Press / EJGO / Volume 26 / Issue 5 / pii/2005213

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Review

Endometrial cancer: asymptomatic endometrial findings. Characteristics of postmenopausal endometrial cancer

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1 Gynecologic Oncology, University of Padua, Italy
2 Department of Gynecology-Obstetrics, Euganea Medica, Italy
3 Department of Pathology, University of Padua, Italy
Eur. J. Gynaecol. Oncol. 2005, 26(5), 479–484;
Published: 10 October 2005

 Endometrial cancer affects patients at every ages, however it occurs more frequently in menopause (> 50) and in postmenopause (> 70). The most cancer frequent affects symptoms patients are at every bleeding age, and however vaginal it occurs discharge. more When frequently hematometra in or menopause pyometra (> 50) is and present m the patient postmenopausemay feel ination pain. or by some histological cases endometrial examination of a adenocarcinoma uterus is surgically asymptomatic removed for and the other diagnosis indications. is casually these made cases the during most ultrasound frequent exam­find­trialings are thickness polyps are and usually abnormally limited to a small area thickness and of the surrounded endometrial by atrophic mucosa. mucosa. Higher postmenopause incidence polyps rates and of abnormal endometrial endome­cancer trial were correlated with polyps estrogen and an inreased or number non-estrogen of serous associated Patients in identified postmenopause in the > 65-age affected group. Endome-trial carcinoma may be estrogen correlated or non-estrogen associated. Patients in postmenopause are often affected by non-estro-gen correlated endometrial carcinoma. According to Kurman and the other authors the first type of endometrial adenocarcinoma(estro-gen correlated) is characterized by low-grade malignancy. On the contrary, non-estrogen correlated neoplasia is more aggressive. In our case series including 102 women >70 years with endometrial carcinoma we found that survival was correlated with stage and grading – early stages were the most frequent and the grade increased with stage. In fact all the patients with relapses had grade 2 or 3 adenocarcinomas. Thirty-one patients > 70 years(30.69%) had a non-endometrioid type of cancer.

Endometrial cancer
Elderly patients
Asymptomatic findings
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