IMR Press / EJGO / Volume 26 / Issue 3 / pii/2005172

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research

Open surgical biopsy for nonpalpable breast lesions detected on screening mammography

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1 Breast Unit – 2nd Department of Propedeutic Surgery, Athens Medical School, Laiko General Hospital, and 2nd Surgical Department, “Vostanio” Hospital, Mytilene, Lesuas Island (Greece)
Eur. J. Gynaecol. Oncol. 2005, 26(3), 311–314;
Published: 10 June 2005

The aim of this retrospective clinical study was the analysis of histologic findings of nonpalpable breast lesions managed by open surgical biopsy. A senes of 630 women underwent 664 preoperatwe locahzauons of nonpalpable, mammograph1cally detected breast lesmns during the last IO-year period. Indications for biopsy were (1) clustered microcalcifications, (2) solid mass, and (3) radiologic parenchymal distortion. The lesions were localized preoperatively using hook-wire methods, and all biopsies were performed under general anesthesia. Histopathology revealed carcinoma in 172 (25.9%) cases; noninvasive in 114 (66.3%) cases and infiltrating in 58 (33.7%) cases. The highest malignancy rate was found in cases with microcalcifications (112 carcinomas out of 323 cases, 34.7%). Lymph node invasion was present in 25% of patients with invasive cancers. The hook-wire localization of nonpalpable breast lesions is a simple, accurate and safe method for detection of early breast cancers. Frozen section is feasible and accurate in the majority of these lesions, and therefore, diagnostic and therapeutic one-step surgical procedures could be performed.

Breast cancer
Stereotactic biopsy
In situ carcinoma
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