IMR Press / EJGO / Volume 25 / Issue 5 / pii/2004249

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research

Normal colposcopy following abnormal Pap smear evoking LGSIL: A follow-up study

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1 Department of Obstetrics and Gynaecology, University Hospital of Patras, Patras (Greece)
2 Department of Pathology-Cytology, University Hospital of Patras, Patras (Greece)
Eur. J. Gynaecol. Oncol. 2004, 25(5), 623–624;
Published: 10 October 2004

The aim of this study was to determine the optimal treatment policy in women presenting with an abnormal Pap smear showing low­grade squamous intraepithelial lesion (LGSlL), who additionally had normal colposcopic findings. We prospectively studied 160 women with LGSIL and normal colposcopy, and divided them into two groups. Group A, consisting of 54 women, was followed-up for a mean period of 42 months and had a new control smear 12 months after the initial one. Group B, consisting of 106 women, was followed-up for a mean period of 44 months and had two consecutive control smears (6 and 12 months after the initial), and a new col­poscopy, depending on the findings. At the end of the first year, the lesion persisted in 37% and 39% of the patients in groups A and B, respectively. At the end of the study, regression or persistence of the LGSIL was revealed in 63% and 61 % of the women in groups A and B, respectively. Aggrava­tion of the lesions occurred after 16.5 and 15 months, respectively, in groups A and B. Our findings suggest that women with LGSIL and normal colposcopy do not need further therapeutic measures during the first year after the initial smear.

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