IMR Press / EJGO / Volume 25 / Issue 5 / pii/2004243

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research

Low-grade cervical squamous intraepithelial lesion during pregnancy: Conservative antepartum management

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1 Discipline of Gynaecology and Obstetrics, Discipline of Special Pathology, Faculty of Medicine of “Tridngulo Mineiro” (FMTM), Uberaba M.G. (Brazil)
Eur. J. Gynaecol. Oncol. 2004, 25(5), 600–602;
Published: 10 October 2004

The purpose of this retrospective study was to determine the regression rate and management of low-grade squamous intraepithelial lesions (LSIL) in pregnancy. Seventy-four women with cytological findings of LSIL were analysed during the pregnant-puerperal period (until 12 months postpartum). Age, parity, cytological and colposcopic findings, route of delivery, and postpartum follow-up were studied. The age and parity of patients ranged (average) from 12 to 32 years (21.2 ± 4.9), 0-5 (0.89 ± 1.14), and 9-32 years (16.1 ± 3.5), respectively. Thirty-nine of 55 (70.9%) and 12 of 19 (63.1%) pregnant women had normal cytology after vaginal delivery and caesarean section, respectively (p > 0.05). In postpartum, eight patients (10.8%) persisted with LSIL and ten (13.5%) presented high­grade squamous intraepithelial lesions. No case of unsatisfactory colposcopy and invasive carcinoma were found. LSIL during preg­nancy has a high rate of regression, regardless of the route of delivery. Conservative management with colposcopic evaluation is pro­posed during gestation.

Low-grade squamous intraepithelial lesion
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